Hair loss and thinning are common problems affecting millions of people worldwide. As the quest for effective treatments continues, Platelet-rich Plasma (PRP) and Platelet-rich Fibrin (PRF) have emerged as promising options. Both are autologous treatments, meaning they utilize a patient's own blood to stimulate hair growth. However, they are not the same. This article delves into the differences between PRP and PRF and their efficacy in treating hair loss.